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See Xenobiotic transporters Antioxidant comeback, 140 Anuria, 180 Apaf-1 role in apoptosome, 113 suppression through Hsp70, 139 AP endonucleases, duty in inferior excision repair, 238 Apoptosis delimitation and determining, 112 induction via DNA mutilation, 238 instrinsic pathway, 115 role in toper cardiac myopathy, 279 role of caspases, 113 Aristolochic acid enzymatic nitroreduction, 250 role in Balkans endemic nephropathy, 248 Aromatic amines, 306 authentic content, 11 Arsenic, 7, 9 self-possession in tobacco smoke, 298 Arylhydrocarbon receptor (AhR) inducing ligands, 132 structural features, 131 toxicity receptor archetype, 94 Aryl hydrocarbon receptor nuclear translocator (ARNT), 131 Asbestos asbestosis in exposed workers, 254 multifariousness of woman forms and individual form, 253 real significance, 11 ATF6 activation pathway, 145 function in ER stress response, 145 ATF4, position in ER significance comeback, 145 Azidothymidine (AZT), hepatotoxic embryonic, 166 B Centre excision patch up (BER), 238 Bcl-2, role in apoptosis, 113 Benzene, alliance with leukemia, 74 Benzoquinone, 74 Biliary excretion, prestige of mass, 82 Bioactivation contributions to carcinogen activation, 231 outlining and toxicological roles, 95 metabolic activation of NNN and NNK, 304 capacity in demon rum toxicity, 265 job in benzene toxicity, 74 task in chloroform nephrotoxicity, 183 r“le in developmental toxicity, 195 function in paracetamol hepatotoxicity, 164 function in the genotoxicity of polycyclic aromatic hydrocarbons (PAH), 301 place in thioacetamide hepatotoxicity, 172 job in trichloroethylene nephrotoxicity, 184 post in troglitazone hepatotoxicity, 168 character in vinyl chloride toxicity, 248 impersonation of electronic properties, 99 capacity of macromolecular selectivity, 98 impersonation of metabolite steadiness, 96 Bisphenol A epigenetic mechanisms in lineage abnormalities, 200 fabrication and manipulation, 214 lines in latent toxicity, 50 British Doctors' Muse about, 293 Burley tobacco, 288 Butadiene (BD), association in tobacco smoke, 308 Butylated hydroxyanisole (BHA), 136 C Cadherins calcium mimicry not later than teratogens, 202 embryonic downregulation by cadmium, 212 role in developmental toxicity, 201 Index The using software is test version. 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